Jonas Brothers, Jelly Roll to perform on ‘Stand Up To Cancer’ TV special

Jonas Brothers 2023 Tour One Night Five Albums - San Antonio, Texas, October 5, 2023 The Jonas Brothers returned to San Antonio on the 2023 Tour One Night Five Albums run, hitting the Frost Bank Center with special guest Lawrence. The big show, big lights, and happy crowd filled the arena, as the Jonas Brothers played all the hits, and more from five of their hit albums! (Johnnie Walker)

By Andrea Dresdale

August 06, 2025 at 1:13 pm EDT

Earlier this year, Jonas Brothers released “I Can’t Lose,” a new song off their Greetings From Your Hometown album, in support of Mastercard’s Stand Up To Cancer campaign. Now the group will headline the annual Stand Up To Cancer fundraising TV special.

The brothers have joined the lineup of the show, which will be hosted by Sheryl Crow, and aired and streamed simultaneously on over 30 platforms across the U.S. on Aug. 15.

In addition to JoBros and Sheryl, the event will feature performances from Jelly Roll, Gavin DeGraw, Noah Cyrus, and country hitmakers Dan + Shay, Jon Pardi and Brothers Osborne. Reese Witherspoon, Keith Urban, Kevin Bacon and Jamie Foxx will appear in pretaped segments.

The special airs at 8 p.m. ET/7 p.m. CT.